Hormones influence every cell and function in the human body. They regulate our metabolism, sexual function, growth, tissue function, and mood among other things. These hormones can easily become imbalanced or even lost due to aging, childbearing, hormones in the foods we eat, stress and other environmental factors. Hormone imbalances can occur at any age and are becoming more prevalent among younger generations. Fortunately these imbalances are fairly easy to correct through Bio-Identical Hormone Replacement Therapy, or BHRT.
Bio-identical hormone replacement therapy uses natural hormones to correct the hormonal imbalance. These natural bio-identical plant derived hormones, such as wild yam root, have been prescribed by European physicians for well over 50 years. The molecular makeup of the replacement hormone is biologically engineered to match the patient’s own naturally produced hormones at the precise level that they need. Because Bio-identical hormones are chemically identical to natural human hormones they are almost entirely free of side effects unlike synthetic hormones.
Estrogen & Progesterone
Estrogen and progesterone balance is crucial to a woman feeling healthy and like herself. Imbalances in these two important hormones can lead to symptoms such as hot flashes, mood swings, night sweats, lack of energy, low sex drive and weight gain. The typical imbalance is that estrogen is too high and progesterone is too low. Along with bio-identical hormone replacement therapy, a healthy gut flora with Omega 3’s will assist estrogen release from the colon, instead of being reabsorbed and stored in the liver.
In men, testosterone begins to decline after the age of 20. By the time a man is 40 he has about half of the testosterone that he did in his 20’s. Symptoms from this decline in testosterone can include a decreased sex drive, loss of energy, irritability, muscle loss or weakness, increased body fat, erectile dysfunction, and memory loss. These symptoms can easily be alleviated by bio-identical hormone replacement therapy.
With the assistance of bio-identical hormone replacement therapy we are finding that the nutritional value in the body is testing stronger. The body is no longer as stressed and needs less outside support than before treatment. So if you are ready to feel healthier and younger take the next step and experience what bio-identical hormone replacement therapy can do for you.
Questions about Pellet Therapy
A pellet is a small rice-sized dose of hormones. Estrogen, Progesterone, and Testosterone are all available in pellet form. Each patient is different and may or may not require all three hormones.
Just like all hormone therapy, pellet dosage is determined by blood labs that are drawn before a pellet appointment. The dosage is then customized for the patient.
Pellet are “implanted” and are often referred to as hormone implants. The doctor makes a tiny incision in the hip area of the patient and uses a special tool called a trochar to place the pellets in the incision in a sterile manner.
For women, pellets typically last about 3 months. For men, pellets typically last about 6 months.
The main advantage of pellets is their time-released nature. The patient does not have to remember to take their hormones daily, they are automatically released and absorbed over months at a time. If the patient travels alot or just has an extremely busy schedule, this hands-off approach can be beneficial.
Pellet Therapy can also be the most cost-effective method for some patients. Paying one cost for hormone therapy every few months can cost less than some prescriptions. Each patient is different and pellet therapy may not be right for everyone.
Sermorelin Therapy Questions & Answers
Sermorelin is a form of growth hormone releasing factor (GRF) that contains only the first 29 amino acids. The GRF that is produced by neurosecretory neurons in the brain contains 44 amino acids. In the 1970s, Nobel Laureates, R. Guilleman and A. Shalley found that only the first 29 amino acids are responsible for stimulating pituitary production and secretion of hGH. Therefore, the chemical name for Sermorelin is GRH 1-29 NH 2.
Sermorelin is a prescription drug, compounded by U.S. pharmacies pursuant to a physician’s prescription and patient self-injected subcutaneously. It stimulates the pituitary gland to naturally produce increased amounts of growth hormone. Sermorelin is a truncated analog of a growth hormone releasing factor (GRF 1-44) that is naturally produced by the brain to stimulate pituitary production of HGH. The increased volume of HGH produced by the pituitary gland causes an increase in the production of Insulin-Like Growth Factor-1 (IGF-1) by the liver and results in the benefits of treatment provided to the adult patient.Your Content Goes Here
As a result of sermorelin therapy, the increased volume of HGH secreted by the stimulated pituitary gland is converted by the liver into IGF-1. The increased amount of IGF-1 in the blood stream results an increase in metabolism and growth of new cells within the body’s organs and bones. This treatment is prescribed for unlabeled use in adults to increase lean muscle mass, reduce body fat, increase bone density, enhance the immune system, and strengthen the heart, as well as, other organs of the body.
And since the increased volume of HGH is produced by the body’s pituitary gland, the body’s endocrine system will not allow more growth hormone to be produced by sermorelin‘s stimulation of the pituitary than the body can safely process within the endocrine self-monitoring system.
Sermorelin therapy has been specifically approved for medical use in increasing growth hormone levels in children deficient in growth hormone production. Its use to increase the growth hormone and IGF-1 levels in adults is an off-label use of this prescription drug.
No, Sermorelin is a growth hormone secretagogue, which means that it stimulates the pituitary gland to produce and secrete growth hormone. Sermorelin is a small peptide containing only 29 amino acids, whereas HGH (human growth hormone) is a much larger molecule containing 191 amino acids.
No, the over the counter “HGH” releasers are usually the amino acids L-arginine, L-glutamine, L-ornithine, glycine, L-dopa, as well as such substances as ornithine alpha-ketoglutarate and the herbs macuna pruriens and tribulus terrestris. While high doses of these compounds sometimes elicit release of HGH from the pituitary gland, the effect is non-specific. In other words, they create a general effect on brain activity, just as exercise does, that sometimes causes HGH to be released. However, the effect is intermittent and unreliable since it does not work through any receptor specific process on the pituitary gland. In addition, high doses of amino acids can produce kidney problems presenting a risk for the regular use of such products. In contrast, Sermorelin initiates its action exactly the same as that used by naturally occurring growth hormone releasing hormone. Furthermore, it has an excellent safety profile with little side effects.
For several reasons, including the fact that it produces the same effects on body composition and other benefits of HGH, but in addition, its effects are regulated at the level of the pituitary gland by negative feedback and by release of somatostatin so that safety concerns associated the HGH overdosing are minimized or completely avoided. Tissue exposure to HGH released by the pituitary under the influence of Sermorelin is episodic not “square wave” preventing tachphylaxis by mimicking normal physiology. By stimulating the pituitary, Sermorelin preserves more of the growth hormone neuroendocrine axis that is the first to fail during aging. Pituitary recrudescence resulting from Sermorelin blocks the cascade of hypophyseal hormone failure that occurs during aging thereby preserving not only youthful anatomy but also youthful physiology, It provides the patient with all the benefits and more of HGH replacement therapy and furthermore, its off label use is not prohibited by federal law.
Currently, the only method for effectively administering Sermorelin is by subcutaneous injection. However, because the molecule is much smaller than HGH, it may someday be possible to successfully administer it through the nasal mucosa using a spray formulation. This hypothesis is currently being tested.
Although the molecules work at different sites in the body (HGH at the liver and Sermorelin at the pituitary), the amount of material needed to be effective in raising serum IGF-1 are approximately the same. HGH is generally prescribed in daily doses of 1-2 international units (IU), while Sermorelin is typically prescribed in doses of 100-300 micrograms per day.
No. Sermorelin therapy is significantly less expensive than HGH therapy. Furthermore, a vial of HGH usually lasts approximately 12-14 days. In contrast, based upon clinical information defining the effective dose for stimulation of the pituitary gland, one multi-dose vial of Sermorelin will be sufficient to last for 15-30 days.
Loss of HGH potency after about six months or more of continuous use is not unusual and is not due to inferior product. It is because injection of HGH elevates blood levels of the hormone to unnaturally high values for several hours each day. In addition, constant stimulation causes increased production of IGF-1, which also has more constant tissue exposure than under normal conditions. These factors causes target tissue receptors to “down regulate” in an attempt to prevent over stimulation by the unnatural exposure to HGH and IGF-1. Under physiological conditions, HGH is released from the pituitary gland in episodes that cause levels to increase and decrease many times throughout the day. Under such conditions, tachyphylaxis or down regulation does not occur since the tissues receptors get time to “rest” between each stimulatory event.
In contrast to HGH therapy, there is no loss of potency with Sermorelin therapy because its action on the pituitary gland is modulated by feedback through somatostatin. This causes HGH to be released from the pituitary in episodes, rather than in “square wave” pharmacological presentation as occurs upon injection of the gene recombinant product. In addition, the pituitary gland up-regulates to stimulation by Sermorelin causing the gland to rejuvenate.
Yes. There are many reports of data in peer-reviewed medical and scientific journals showing that Sermorelin also has a direct effect on the brain to promote non-REM slow wave sleep.
Sermorelin is administered by injection once daily prior to bedtime. The time of injection is important because the additional GRF provided by Sermorelin complements that which naturally occurs during sleep and thereby facilitates the nocturnal release of HGH that is characteristic of youth. Dose selection should be suited for each person’s individual needs. Sermorelin for injection is available in multi-dose vials containing sufficient product for 15-30 days of Sermorelin therapy.